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pentobarbital will decrease the extent or impact of alosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unfamiliar.pentobarbital will lessen the extent or outcome of flurbiprofen by affecting hepatic enzyme CYP2C9/10 metabolism. Small/Significance Unidentified.Reserve concomitant prescribing of those drugs in clie